(linaclotide) is a guanylate cyclase-C agonist used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) in adults.

Common of Linzess include:

  • ,
  • stomach/abdominal pain or discomfort,
  • gas,
  • bloating,
  • heartburn,
  • vomiting,
  • headache, or
  • cold symptoms such as stuffy nose, sneezing, or sinus pain.

The recommended dose of Linzess for those with irritable bowel syndrome (IBS) is 290 mcg taken once a day on an empty stomach, at least 30 minutes before the first meal of the day. The same applies for those with chronic idiopathic constipation only the dosage is 145 mcg. Pediatric patients under the age of 17 should not take Linzess. Linzess may interact with other drugs. Tell your doctor all medications you use. Linzess should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when Linzess is administered to nursing women. Consult your doctor before breastfeeding.

Our Linzess (linaclotide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur.

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